6-APDB�(also known as�6-(2-aminopropyl)-2,3-dihydrobenzofuran�or�4-Desoxy-MDA) is a�stimulant�and�entactogenic�research chemical�of the�phenethylamine�and�benzofuran�classes.5-apdb,6-apb source,5-apb legal status usa,2-aminopropylbenzofuran
It is a closely related synthetic analogue of�MDA�and�6-APB�and broadly shares the characteristics of serotonin-selective triple�monoamine releasers�and�reuptake inhibitors�associated with other�entactogenic�or�empathogenic�compounds.
6-APDB was first synthesized and studied along with�5-APDB�in 1993 by�David E. Nichols�as a potential non-neurotoxic alternative to�MDMA.
It did not come into popular recreational use until over a decade later, where it briefly entered the rave scene and global research chemicals market, in particular the “legal highs” market in the U.K., before its sale and import were subsequently banned.5-apdb,6-apb source,5-apb legal status usa,2-aminopropylbenzofuran
Because 6-APDB and other substituted benzofurans have not been explicitly outlawed in some countries, they are often technically legal, contributing to their popularity as a substitute or replacement for serotonergic entactogens like MDMA or MDA, and are typically distributed through the online research chemicals grey market.
6-APDB, also known as 6-(2-aminopropyl)-2,3-dihydrobenzofuran, is a synthetic molecule of the�benzofuran�family. Molecules of this class contain a�phenethylamine�core bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at R?.
6-APDB does not contain a methyl substitution on RN, a motif which it shares with�MDA. It is an analogue of MDA where the heterocyclic 4-position oxygen from the 3,4-methylenedioxy ring has been replaced with a methylene bridge. 6-APDB shares this furan ring with�5-APDB,�5-MAPDB�and�6-MAPDB.