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pentedrone

150.002,800.00

pentedrone buy a lesser-known novel�stimulant�substance of the�cathinone�class of substituted cathinones,pentedrone erowid,effects,dosage,vs hexedrone

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Description

Pentedrone�(also known as�drone) is a lesser-known novel�stimulant�substance of the�cathinone�class. Pentedrone belongs to a group of compounds known as�substituted cathinones.pentedrone buy,pentedrone erowid,effects,dosage,vs hexedrone

Pentedrone acts as a�norepinephrine-dopamin�reuptake inhibitor�(NDRI).

Pentedrone was first detected being sold online in 2010. It is an example of a contemporary�designer drug�specifically chosen to mimic and/or replace the effects of street drugs like�cocaine,�MDMA, or�methamphetamine.

Pentedrone and similar compounds are sometimes referred to as “bath salts”.

Pentedrone is known to come in the form of either a white powder or crystallized shards

which users can ingest to produce a powerful, fast-acting but short-lived euphoric stimulant effects which are comparable to those of�crack-cocaine,�N-ethylpentedrone�and�a-PVP-type compounds, particularly when they are�insufflated,�vaporized�or�injected.

Starting with the advent of�MDPV, research chemical stimulants like pentedrone have gained notoriety for its tendency to induce�compulsive redosing�and addictive behaviors in a seemingly significant percentage of its users as well the ability to readily induce�paranoid,�delusional states�and�stimulant psychosis�when abused.[citation needed]

Little data exists about the toxicity and abuse potential of pentedrone in humans. Due to its novelty and brief history of human usage, all information related to this compound should be treated with extreme caution.

It is strongly recommended that one use�harm reduction practices�if using this substance.

Due to the lack of research regarding the substance, all proceeding discussion regarding the pharmacology of this compound derives from speculation based upon its structure and subjective effect similarities to other�cathinones�and related molecules, such as�prolintane,�a-PVP,�a-PHP�and analogs like�N-ethyl-(nor)-pentedrone�(i.e.�NEP).pentedrone buy,pentedrone erowid,effects,dosage,vs hexedrone

Unlike many other substituted cathinones, which display both�reuptake-inhibition�and�releasing agent�properties, pentedrone has been shown to act as a pure�reuptake inhibitor�for the major�catecholamine�neurotransmitters�dopamine�and�norepinephrine, with very modest activity on�serotonin. This renders its pharmacological activity similar to that of�methylphenidate,�cocaine�or�MDPV�(although the latter two possess heavy additional�serotonergic activity.Hexedrone

These pure uptake inhibitors likely do not enter the intracellular space of the synapse via the transporter, which may be associated with less intracellular pharmacological effects and toxicity compared with substrate-type releasers.

This enables the endogenous neurotransmitters dopamine and norepinephrine to accumulate within various synaptic regions in the brain, resulting in�stimulating�and�euphoric effects.pentedrone buy,pentedrone erowid,effects,dosage,vs hexedrone

Notably, the addition of an ethyl group to the terminal amine (-NH2) group of the pentedrone molecule seems to increase its potency significantly, as is observed with its successor analog�N-ethyl-(nor)-pentedrone�(i.e.�NEP) which is viewed as having preferential recreational properties.

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