infochemplaza.gubpharm.com
number
Sale!

Pravadoline

150.00200.00

Pravadoline is a nonacidic, aminoalkylindole analgesic agent that inhibits cyclooxygenase.1 Like NSAIDs, pravadoline inhibits prostaglandin synthesis (IC50 = 5 μM in mouse brain microsomes) and displays antinociceptive activity (ED50 = 26 mg/kg in an acetylcholine-induced writhing assay in mice).
Clear
SKU: ChP01080 Category: Tags: , , , ,

Description

Pravadoline

Pravadoline is a nonacidic, aminoalkylindole analgesic agent that inhibits cyclooxygenase.1 Like NSAIDs, pravadoline inhibits prostaglandin synthesis (IC50 = 5 μM in mouse brain microsomes) and displays antinociceptive activity (ED50 = 26 mg/kg in an acetylcholine-induced writhing assay in mice).1 In contrast to NSAIDs, pravadoline inhibits neuronally stimulated contractions in mouse vas deferens preparations (IC50 = 0.45 μM), an effect similar to that which is produced by opioid analgesics, yet is not attenuated by the opioid receptor antagonist, naloxone.1 Pravadoline does not produce gastrointestinal irritation following acute or chronic administration to rodents.1

CAS Number:92623-83-1
Chemical and physical data
Formula C23H26N2O3
Molar mass 378.46 g/mol

ChemicalPlaza is a worldwide leader since 2010 in the distribution of Research Chemicals as well as an international research chemicals manufacturing company. We work along side a highly professional laboratory mainly creating custom synthesis, research, and pharmaceutical chemicals.

At this time, we have warehouses in Hong Kong, China, Ukraine and EU from where all products are dispatched. Our highly developed distribution network guarantees that all products you receive will be on time and will be sent to the most convenient locations for pickup,and delivery to your scheduled destination,we are expeditious and reliable . Customers satisfaction is our ultimate goal, and we are to serve our customers , make a wise decision by making all your order from ChemicalPlaza you are guaranteed of prompt supply of all your orders to your given address .We also provide various shipping services that deliver products to our clients in various markets and in many different locations around the globe.All products found on this website are sold for the sole purpose of research and education. None of our products is sold for human or animal consumption or for any type of illegal usage.
ChemicalPlaza.lookchem.com

JWH-073

Additional information

WeightN/A
Choose quantity

10-mGrams, 20-mGrams, 25-mGrams, 5-mGrams