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UR-144

150.002,100.00

UR-144 is a potent synthetic cannabinoid (CB) which preferentially binds the peripheral CB2 receptor (Ki = 1.8 nM) over the central CB1 receptor (Ki = 150 nM).1 UR-144 N-(5-chloropentyl) analog differs from UR-144 by having a chlorine atom on the terminal carbon of the alkyl group.
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Description

UR-144 is a potent synthetic cannabinoid (CB) which preferentially binds the peripheral CB2 receptor (Ki = 1.8 nM) over the central CB1 receptor (Ki = 150 nM).1 UR-144 N-(5-chloropentyl) analog differs from UR-144 by having a chlorine atom on the terminal carbon of the alkyl group. The biological activities of this compound have not been characterized. ur-144 for sale,ur 144f,xlr-11 for sale,jwh-018,fab-144

This product is intended for forensic and research applications.

CAS Number:1199943-44-6
Chemical and physical data
Formula C21H29NO
Molar mass 311.461 g/mol

THJ2201

UR-144 has high affinity for the CB2�receptor with a Ki�of 1.8 nM but 83x lower affinity for the CB1�receptor with a Ki�of 150 nM.

�UR-144 was found to possess an EC50�of 421 nM for human CB1�receptors, and 72 nM for human CB2�receptors.UR-144 produces�bradycardia�and hypothermia in rats at a dose of 10�mg/kg, suggesting weak cannabinoid-like activity.

Chemically it is closely related to other 2,2,3,3-tetramethylcyclopropyl synthetic cannabinoids like�A-796,260�and�A-834,735�but with a different substitution on the 1-position of the indole core, in these compounds its 1-pentyl group is replaced with alkylheterocycles like 1-(2-morpholinoethyl) and 1-(tetrahydropyran-4-ylmethyl).

UR-144 is a synthetic cannabinoid that�s been sold as a member of the novel psychoactive substances (NPS) market. It produces some cannabis-like effects, though there�s a lack of information about its activity.JWH-210

We know the drug works at CB1 and CB2 receptors. ur-144 for sale,fab-144

Those actions seem to result in�an effect profile reminiscent of THC and other synthetic cannabinoids. It�s considered more �psychedelic� than some other drugs in the category, but psychedelic-like effects haven�t been reported by all users.ur 144f,xlr-11 for sale,jwh-018

Inhalation (tentative due to a lack of information)

  • Range: 2.5 to 20 mg

Most people have been exposed to the drug in the form of �blends� that contain varying levels of UR-144. It�s not wise to use those products.AM630

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